Boron and medications.
Boron is in the Distil supplement database, evidence Grade C. The page below lists every medication we have explicitly assessed it against.
Boron is a trace mineral often sold for testosterone and bone support, and the honest position on both claims is weaker than the marketing. We no longer recommend it for either. On testosterone, the only randomised trial our literature search found, by Ferrando in 1993, gave 19 male bodybuilders 2.5mg daily or placebo for seven weeks and found no effect of boron on total or free testosterone, lean mass or strength; the positive report people cite is a one-week study in eight men with no control group. On bone, no study in our records measures a bone outcome at all, and the paper usually pointed to is a narrative review. What survives is a Grade C cognitive signal, which rests on mechanism rather than trials, and one genuinely useful property: boron extends the half-life of vitamin D3, which can make it a sensible add-on for someone who is D3 deficient. Typical doses are 3 to 6mg daily, and it is well tolerated in that range. In Great Britain the forms allowed in food supplements are sodium borate and boric acid, so those are the names to look for on a UK label. We lowered our own ceiling from 10mg in August 2026, because the 10mg figure widely quoted as a safe limit is EFSA's tolerable upper intake level, and that covers boron from food and supplements together rather than from supplements alone. Ordinary diet supplies somewhere around 1.5 to 3.5mg a day, so a 10mg supplement would tend to take most people past the limit rather than up to it. Higher amounts are a different story: above 20mg can cause stomach upset and nausea, and very high intakes risk genuine toxicity. You may see that 10mg ceiling described as a UK limit on what is safe to take as a supplement, and both halves of that are wrong: the figure is EFSA's, and as above it covers what you eat as well as what you add. There are no major drug interactions flagged at supplemental doses. If you take it, take it for the D3 support, not for hormones or bone.
We have not yet completed an explicit assessment of medications for Boron in the Distil interactions database. We surface this distinction deliberately: the Distil checker tells you when we have explicitly assessed a pair and when we have not, because both are useful information. If you take Boron alongside a medication, the checker below will surface anything already in our database, and the missing-item form at the bottom of the page routes uncatalogued pairs into our next curation pass.
What this list does not say. Pairs not flagged here are not implicitly safe. They are either not yet in our database, or fall outside our inclusion scope. Use the checker below to surface any medication, and submit a missing item if you take something we have not catalogued.
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How we grade severity, choose what's in scope, and what we exclude.
Every call on this page is reasoned. We publish the full rubric for severity tiers, the medication inclusion logic, the evidence grades we accept, and what we deliberately leave out. About three thousand words. Worth reading once if you use this tool more than occasionally.
Read the full methodologyA full supplement review, built around you, not a generic stack.
The free checker answers one interaction question at a time. A Distil report reviews the bigger picture: your goals, diet, medications, current supplements and any blood results you provide, then shows what appears worth keeping, changing, adding or leaving out.
- what your diet already covers, so you are not adding a capsule for something food is already handling
- which evidence-graded compounds are worth considering for your goals, and which were considered but left out
- what to keep, change or stop from what you already take, plus the order to introduce anything new
- how your medications and complete supplement stack fit together, with daily timing and a clear point for reassessment
The interaction check is one section of the full report. You also get the reasoning behind each recommendation and the evidence references used.
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If a supplement or medication you take isn't in our autocomplete, tell us. We go through what people flag every week and add what's missing.