Distil
Journal

Evidence-led analysis

Honest, cited reads on the supplements people actually take. We sell no supplements, so nothing here is a sales pitch: just the evidence, and what it does and does not support.

Industry
Autophagy and supplements: what actually switches it on

Autophagy is real, and the switch that controls it responds to fasting, exercise and weight, not to a capsule. What the spermidine and urolithin A evidence does and does not show.

Industry
Does vitamin B1 fix IBS? What the study actually found

A 2026 genetics study in Gut linked vitamin B1 metabolism to gut motility and IBS. It is a GWAS and a dietary association, not a trial showing B1 treats IBS. What the evidence does and does not say.

Compound
PEA for IBS: what the trials actually show

Palmitoylethanolamide (PEA) is one of the few IBS supplements with real randomised trials. What they show, what they do not, and why it sits at Grade B: promising, not proven.

Topical
Staying healthy on the weight-loss jabs

Ozempic, Wegovy and Mounjaro take the weight off, but some of it is muscle. What the evidence actually says: the 40% headline is overstated, and protein plus resistance training are the two levers that matter.

Data
Most-prescribed UK drugs and their supplement interactions

At least 19 of England

Field notes
What actually moved our search indexing from 22 pages to 354

Google had indexed 22 of our pages. Eight days later it was 354. The honest version: four separate pieces of work, done weeks apart, that only paid off when the last one landed. A builder

Industry
Both sides were right: what the ZOE/ASA ruling shows about how supplements get sold

A UK regulator told ZOE its Daily30+ ad could not say

Compound deep-dive
The form is the molecule

Why the back of a supplement bottle tells you more than the front. Magnesium, folate, omega-3, vitamin D and curcumin: the form on the label is the dose your body actually sees.

Methodology
How we grade evidence

A, B, C, D, and the list we publish but never recommend. How Distil grades every supplement compound on published evidence, why the grade has to be per-form not per-name, and why the rejection list is the real product.

Manifesto
Why I built Distil

A supplement report business that doesn