Distil
Journal

Evidence-led analysis

Honest, cited reads on the supplements people actually take. We sell no supplements, so nothing here is a sales pitch: just the evidence, and what it does and does not support.

Health
Lipitor and supplements: the CoQ10 question, and the one that is secretly a second statin

Two things people believe about Lipitor and supplements are backwards. The CoQ10 everyone takes may not help, and red yeast rice is a statin in disguise.

Health
Synthroid and supplements: the timing rule, and the two interactions nobody mentions

Everyone knows to space calcium and iron away from Synthroid. Two other supplement interactions get missed: one moves your thyroid level, one fakes your blood test.

Health
Ozempic and supplements: what actually interacts, and the bigger thing to watch

Ozempic barely interacts with supplements, it is not cleared by the liver enzymes that cause interactions. The real supplement issue is what eating far less leaves out.

Health
Warfarin and supplements: the vitamin K myth, and what actually interacts

The warfarin advice everyone repeats, avoid leafy greens, is half wrong. The real rule is consistency, and the interactions that actually raise your risk are the supplements nobody warns you about.

Health
Zoloft and supplements: the ‘natural’ mood boosters that clash with your antidepressant

The natural mood supplements sold side by side, St John's Wort, 5-HTP, SAMe, are the exact ones to check against Zoloft. Two are a hard stop. Here is why.

Industry
Autophagy and supplements: what actually switches it on

Autophagy is real, and the switch that controls it responds to fasting, exercise and weight, not to a capsule. What the spermidine and urolithin A evidence does and does not show.

Industry
Does vitamin B1 fix IBS? What the study actually found

A 2026 genetics study in Gut linked vitamin B1 metabolism to gut motility and IBS. It is a GWAS and a dietary association, not a trial showing B1 treats IBS. What the evidence does and does not say.

Compound
PEA for IBS: what the trials actually show

Palmitoylethanolamide (PEA) is one of the few IBS supplements with real randomised trials. What they show, what they do not, and why it sits at Grade B: promising, not proven.

Topical
Staying healthy on the weight-loss jabs

Ozempic, Wegovy and Mounjaro take the weight off, but some of it is muscle. What the evidence actually says: the 40% headline is overstated, and protein plus resistance training are the two levers that matter.

Data
Most-prescribed UK drugs and their supplement interactions

At least 19 of England's 25 most-prescribed medicines have a common supplement that interacts with them, lined up against real NHS prescribing volumes.

Field notes
What actually moved our search indexing from 22 pages to 354

Google had indexed 22 of our pages. Eight days later it was 354. The honest version: four separate pieces of work, done weeks apart, that only paid off when the last one landed. A builder's field note on Crawled-currently-not-indexed.

Industry
Both sides were right: what the ZOE/ASA ruling shows about how supplements get sold

A UK regulator told ZOE its Daily30+ ad could not say 'just real food.' Both the ASA and Tim Spector were right, and both missed the structural point: every word on a supplement package has to be defensible to a regulator and meaningful to a shopper at once.

Compound deep-dive
The form is the molecule

Why the back of a supplement bottle tells you more than the front. Magnesium, folate, omega-3, vitamin D and curcumin: the form on the label is the dose your body actually sees.

Methodology
How we grade evidence

A, B, C, D, and the list we publish but never recommend. How Distil grades every supplement compound on published evidence, why the grade has to be per-form not per-name, and why the rejection list is the real product.

Manifesto
Why I built Distil

A supplement report business that doesn't sell supplements. The reasoning behind Distil's anti-funnel design, the rules behind the personalisation, and a look inside the coordination most stacks don't do.