Supplements and Insulin aspart.
Insulin aspart, sold under the brand names NovoRapid, Fiasp, Trurapi, is insulin replacement therapy for type 1 or insulin-requiring type 2 diabetes.
Insulin aspart is insulin replacement therapy. It is used universally in type 1 diabetes and in type 2 diabetes that has progressed to needing insulin. The supplement surface is small, because insulin is a peptide with no CYP metabolism and no plasma protein displacement story. The clinically important issue is anything that affects glucose handling. Berberine. Cinnamon (at habitual food amounts not clinically significant; at extract doses a small additive effect). Chromium at high doses. Alpha lipoic acid. And the GLP-1 mimetic supplement category. All carry small additive glycaemic effects that, stacked on top of an insulin regimen, can drive hypoglycaemia. Patients on insulin who add such a supplement benefit from more frequent glucose monitoring in the first two to four weeks of the change. Vitamin B12 status matters too, because most Type 2 patients carry metformin alongside their insulin.
Below are the 3 documented pairs we have explicitly assessed against Insulin aspart in the Distil database: 3 caution. The pairs cluster around 1 mechanism: Additive glucose lowering. Every call is cited to either a clinical reference (PMID) or the British National Formulary. Anything not on this list is either still to be assessed or beyond our database scope. The checker beneath surfaces assessments by supplement, and the missing-item form at the bottom of the page routes any uncatalogued supplement into our next curation pass.
Documented interactions
Last reviewed 14 June 2026. Each interaction below lists the evidence its assessment drew on: some rest on studies of the exact pair, others on mechanism evidence, where a citation may support one part of the reasoning rather than the exact combination. The evidence line on each entry says which.
Additive glucose lowering
Caution Does Alpha Lipoic Acid interact with Insulin aspart?
Alpha lipoic acid may improve how your body responds to insulin, which can lower blood sugar on top of the insulin you inject. This may increase the chance of glucose going too low. If you take alpha lipoic acid with insulin, monitor your blood glucose closely, especially early on, and your doctor may need to reduce your insulin dose.
Evidence: Supported by human study data.
Reviewer-flagged: awaiting clinical-reviewer sign-off.
Caution Does Holy Basil interact with Insulin aspart?
Holy basil (tulsi) may lower blood sugar on its own, on top of the insulin you inject. This may increase the chance of glucose going too low. If you take holy basil with insulin, monitor your blood glucose closely, especially early on, and your doctor may need to reduce your insulin dose.
Evidence: Limited human data, from small studies or case reports.
Reviewer-flagged: awaiting clinical-reviewer sign-off.
Caution Does NMN interact with Insulin aspart?
Taking NMN while you inject insulin could in theory lower blood sugar more than your current dose is set for, because NMN may modestly improve how your body responds to insulin. This has not been studied directly. If you take both, monitor your blood sugar and speak to your diabetes team before starting.
Evidence: No direct study of this exact combination yet; the caution rests on a plausible mechanism or on reports involving a related medicine.
Reviewer-flagged: awaiting clinical-reviewer sign-off.
What this list does not say. Pairs not flagged here are not implicitly safe. They are either not yet in our database, or fall outside our inclusion scope (food-supplement interactions only; for drug-drug interactions, the BNF is authoritative). Use the checker below to surface any supplement, and submit a missing item if you take something we have not catalogued.
No affiliates. No commission. We earn nothing on what you buy.
How the checker decides
Every result has a source
Each pair we have assessed is cited to a published study (PMID) or the British National Formulary, so you can read the source yourself.
Four kinds of answer
Severe, caution, no known interaction, and not yet assessed. A pair we have not assessed is never shown as clear.
- Severe
- Caution
- No known interaction
- Not yet assessed
Nothing in our data is not a clearance
When nothing in our data records a problem with a pair, the result says no known interaction at typical doses, which is not a clearance: your pharmacist or GP can check the pair against your full medical history.
A full supplement review, built around you, not a generic stack.
The free checker answers one interaction question at a time. A Distil report reviews the bigger picture: your goals, diet, medications, current supplements and any blood results you provide, then shows what appears worth keeping, changing, adding or leaving out.
- what your diet already covers, so you are not adding a capsule for something food is already handling
- which evidence-graded compounds are worth considering for your goals, and which were considered but left out
- what to keep, change or stop from what you already take, plus the order to introduce anything new
- how your medications and complete supplement stack fit together, with daily timing and a clear point for reassessment
The interaction check is one section of the full report. You also get the reasoning behind each recommendation and the evidence references used.
£49 until 30 June 2027 · £79 from 1 July 2027.
Something missing?
If a supplement or medication you take isn't in our autocomplete, tell us. What people flag joins the queue of what we add next.