Omega-7 and medications.
Omega-7 is in the Distil supplement database, evidence Grade C. The page below lists every medication we have explicitly assessed it against.
Omega-7, mainly palmitoleic acid from sea buckthorn oil, is a fatty acid taken for mucosal membrane health, with interest in metabolic support. The evidence now sits at Grade C across the board, and it is worth being plain about why. The strongest single result is the menopause niche: one placebo-controlled trial in 116 postmenopausal women found oral sea buckthorn oil may improve the integrity of the vaginal lining, though it used 3g a day, well above the usual supplement dose. The gut-lining use rests on mechanism rather than trials: no trial in our records measures a gut outcome, and the dry-eye and vaginal findings belong to those surfaces, not the bowel. On the metabolic side, the pooled analysis of fifteen trials found modest lipid improvements only in people whose lipids were already abnormal, and no effect at all on blood sugar, blood pressure or weight, so the claim that palmitoleic acid improves how the body handles blood sugar is not supported; the one human trial behind it was retracted. The typical dose is 210 to 500mg of sea buckthorn oil daily. It is most relevant for peri- and post-menopausal women dealing with dryness. No significant interactions are documented, and it is well tolerated, with occasional mild stomach upset the main complaint. A practical note: mucosal benefits build slowly, so give it two to three months before judging the effect.
We have not yet completed an explicit assessment of medications for Omega-7 in the Distil interactions database. We surface this distinction deliberately: the Distil checker tells you when we have explicitly assessed a pair and when we have not, because both are useful information. If you take Omega-7 alongside a medication, the checker below will surface anything already in our database, and the missing-item form at the bottom of the page routes uncatalogued pairs into our next curation pass.
What this list does not say. Pairs not flagged here are not implicitly safe. They are either not yet in our database, or fall outside our inclusion scope. Use the checker below to surface any medication, and submit a missing item if you take something we have not catalogued.
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How we grade severity, choose what's in scope, and what we exclude.
Every call on this page is reasoned. We publish the full rubric for severity tiers, the medication inclusion logic, the evidence grades we accept, and what we deliberately leave out. About three thousand words. Worth reading once if you use this tool more than occasionally.
Read the full methodologyA full supplement review, built around you, not a generic stack.
The free checker answers one interaction question at a time. A Distil report reviews the bigger picture: your goals, diet, medications, current supplements and any blood results you provide, then shows what appears worth keeping, changing, adding or leaving out.
- what your diet already covers, so you are not adding a capsule for something food is already handling
- which evidence-graded compounds are worth considering for your goals, and which were considered but left out
- what to keep, change or stop from what you already take, plus the order to introduce anything new
- how your medications and complete supplement stack fit together, with daily timing and a clear point for reassessment
The interaction check is one section of the full report. You also get the reasoning behind each recommendation and the evidence references used.
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