Supplements and Bisoprolol.
Bisoprolol, sold under the brand names Cardicor, Emcor, is a beta-blocker: it reduces heart rate and cardiac output by antagonising beta-adrenergic receptors.
Bisoprolol is a beta-blocker selective for the beta-1 receptor, and the most prescribed agent in this class in England. The drug slows heart rate. Uses are hypertension, stable angina, and at lower doses heart failure with reduced ejection fraction. The selectivity for beta-1 over beta-2 is relative, not absolute, so the asthma caution carries: bronchospasm risk rises as the dose climbs and the drug starts to touch airway receptors as well. Two cardiac interactions are worth flagging on the supplement side. The first is additive bradycardia, where CoQ10's effect is small and clinically minor while vagally active compounds matter more. The second is additive hypotension, where beetroot, hibiscus, and garlic stack on the BP side. Bisoprolol is not strongly CYP metabolised, so the CYP interactions are quieter than with statins or SSRIs. Watch in the early weeks for a resting heart rate below 50, or symptomatic dizziness on standing. Either warrants a GP review of dose rather than supplement adjustment.
Below are the 1 documented pair we have explicitly assessed against Bisoprolol in the Distil database: 1 amber. The pairs cluster around 1 mechanism: Additive blood-pressure lowering. Every call is cited to either a clinical reference (PMID) or the British National Formulary. Anything not on this list is either still to be assessed or beyond our database scope. The checker beneath surfaces assessments by supplement, and the missing-item form at the bottom of the page routes any uncatalogued supplement into our next curation pass.
Documented interactions
Additive blood-pressure lowering
Beetroot lowers blood pressure through the nitric oxide pathway, and bisoprolol lowers blood pressure through beta-1 receptor blockade. Used together, the combined blood-pressure effect is mild but real. Watch for dizziness on standing, especially in the first two weeks. If symptoms appear, tell your GP.
What this list does not say. Pairs not flagged here are not implicitly safe. They are either not yet in our database, or fall outside our inclusion scope (food-supplement interactions only; for drug-drug interactions, the BNF is authoritative). Use the checker below to surface any supplement, and submit a missing item if you take something we have not catalogued.
For adults over 18.
This tool gives evidence-graded information, not medical advice. Always discuss changes with your GP, pharmacist, or specialist before making them, especially if you take any medication, are pregnant, breastfeeding, or have a serious health condition.
How we grade severity, choose what's in scope, and what we exclude.
Every call on this page is reasoned. We publish the full rubric for severity tiers, the medication inclusion logic, the evidence grades we accept, and what we deliberately leave out. About three thousand words. Worth reading once if you use this tool more than occasionally.
Read the full methodologySomething missing?
If a supplement or medication you take isn't in our autocomplete, tell us. We go through what people flag every week and add what's missing.