Supplements and blood pressure medication.
Blood pressure medications fall into four common classes (ACE inhibitors like ramipril, ARBs like losartan, beta-blockers like bisoprolol, calcium channel blockers like amlodipine) plus diuretics like furosemide. Several supplements lower blood pressure on their own, which is sometimes useful and sometimes risky depending on baseline control.
The additive-BP-lowering supplements with the strongest evidence are magnesium, garlic extract, hibiscus, CoQ10 and beetroot/nitrate. On a well-controlled regimen these can be helpful; on a borderline-low BP they can tip into orthostatic hypotension. With an ACE inhibitor or an ARB, potassium is the one to avoid: both make the body hold on to potassium, so a potassium supplement (or a high-potassium multi) can push it high enough to affect heart rhythm. Do not add one unless your GP has advised it and is checking your blood potassium.
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How the checker decides
Every result has a source
Each pair we have assessed is cited to a published study (PMID) or the British National Formulary, so you can read the source yourself.
Four kinds of answer
Severe, caution, no known interaction, and not yet assessed. A pair we have not assessed is never shown as clear.
- Severe
- Caution
- No known interaction
- Not yet assessed
Nothing in our data is not a clearance
When nothing in our data records a problem with a pair, the result says no known interaction at typical doses, which is not a clearance: your pharmacist or GP can check the pair against your full medical history.
A full supplement review, built around you, not a generic stack.
The free checker answers one interaction question at a time. A Distil report reviews the bigger picture: your goals, diet, medications, current supplements and any blood results you provide, then shows what appears worth keeping, changing, adding or leaving out.
- what your diet already covers, so you are not adding a capsule for something food is already handling
- which evidence-graded compounds are worth considering for your goals, and which were considered but left out
- what to keep, change or stop from what you already take, plus the order to introduce anything new
- how your medications and complete supplement stack fit together, with daily timing and a clear point for reassessment
The interaction check is one section of the full report. You also get the reasoning behind each recommendation and the evidence references used.
£49 until 30 June 2027 · £79 from 1 July 2027.
Something missing?
If a supplement or medication you take isn't in our autocomplete, tell us. What people flag joins the queue of what we add next.