Supplements and antiplatelet drugs.
Antiplatelet drugs (aspirin, clopidogrel) reduce platelet aggregation. A category of supplements does the same. Combining them is rarely catastrophic at typical doses but the risk profile shifts, especially around surgery, dental work, or any procedure where bleeding control matters.
Supplements with documented additive antiplatelet effects: garlic extract (allicin-standardised), ginkgo biloba, ginger at higher doses, fish oil at higher EPA/DHA, and high-dose vitamin E. The standard surgical rule is to stop these six weeks before any planned procedure. Curcumin and CoQ10 are sometimes named here, but the evidence for those two is weaker; they appear in the Amber tier as monitor-rather-than-stop.
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How we grade severity, choose what's in scope, and what we exclude.
Every call on this page is reasoned. We publish the full rubric for severity tiers, the medication inclusion logic, the evidence grades we accept, and what we deliberately leave out. About three thousand words. Worth reading once if you use this tool more than occasionally.
Read the full methodologyA full supplement review, built around you, not a generic stack.
The free checker answers one interaction question at a time. A Distil report reviews the bigger picture: your goals, diet, medications, current supplements and any blood results you provide, then shows what appears worth keeping, changing, adding or leaving out.
- what your diet already covers, so you are not adding a capsule for something food is already handling
- which evidence-graded compounds are worth considering for your goals, and which were considered but left out
- what to keep, change or stop from what you already take, plus the order to introduce anything new
- how your medications and complete supplement stack fit together, with daily timing and a clear point for reassessment
The interaction check is one section of the full report. You also get the reasoning behind each recommendation and the evidence references used.
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Something missing?
If a supplement or medication you take isn't in our autocomplete, tell us. We go through what people flag every week and add what's missing.