Supplements and antiplatelet drugs.
Antiplatelet drugs (aspirin, clopidogrel) reduce platelet aggregation. A category of supplements does the same. Combining them is rarely catastrophic at typical doses but the risk profile shifts, especially around surgery, dental work, or any procedure where bleeding control matters.
Supplements with documented additive antiplatelet effects: garlic extract (allicin-standardised), ginkgo biloba, ginger at higher doses, fish oil at higher EPA/DHA, and high-dose vitamin E. The standard surgical rule is to stop these six weeks before any planned procedure. Curcumin and CoQ10 are sometimes named here, but the evidence for those two is weaker; they appear in the Amber tier as monitor-rather-than-stop.
How we grade severity, choose what's in scope, and what we exclude.
Every call on this page is reasoned. We publish the full rubric for severity tiers, the medication inclusion logic, the evidence grades we accept, and what we deliberately leave out. About three thousand words. Worth reading once if you use this tool more than occasionally.
Read the full methodologyWant this checked across everything you take?
This page checks the pairs you enter. The personalised Distil report goes further:
- the same graded, cited interaction check across your whole stack, not just the pairs you thought to type in
- where your current routine may be leaving you short of your goals
- the evidence-backed compounds worth adding, and the ones worth dropping
It's a paid report: £79, or £49 for the first 25 customers. The interactions check is one section of it, and you can read a real one in full before you buy.
See a real sample reportSomething missing?
If a supplement or medication you take isn't in our autocomplete, tell us. We go through what people flag every week and add what's missing.